01
Financial donations
Cover infrastructure, sequencing, storage, scientific validation and grants for researchers. Every dollar shows up in monthly public reports.
HAS + LIFE
More good years of life, lived to the fullest.
A common cause for all of humanity · Open science · Come and join
More years to enjoy life — unhurried, healthy, with the people we love — and an open system where every person on the planet can contribute.
Human Aging Simulators (HAS) integrates financial donations, clinical data, discoveries and technology into one open platform. Every contribution — from a person, a researcher or a donor — adds up to the same goal: extending the good years of human life, together.
- One global goal
- Extend the healthy lifespan of the human species
- Three kinds of contribution
- Financial donation, personal data, discoveries and systems
- 100% open science
- MIT/Apache code · CC-BY data and content
- Ethical governance
- Dynamic consent, bioethics committee, external audit
The mission
A longer, healthier life is within reach. We just have to build it together.
Today information about longevity is fragmented: private labs, closed papers, datasets that don't talk to each other, devices that don't share metrics, countries that don't even compare their populations. That's lost time our species can't afford to keep losing.
Human Aging Simulators (HAS) proposes the opposite: a single, open, reproducible system where anyone — wherever they live, whatever they have — can contribute financial donations, data, discoveries or technology. And where every contribution adds up to the same goal: making it normal, not exceptional, to live 90, 100 or 110 years in good health.
We don't compete with medicine or pharma. We build the shared infrastructure all of humanity can use to understand, measure and modify aging. And we build it together, in public, step by step.
Build scientific models capable of simulating and understanding the human body to accelerate biomedical discoveries.
The life we are building
Picture yourself reaching 100 with a clear mind, strong muscles, your people close, and all the time in the world to enjoy the journey.
We are not trying to prolong old age. We are trying to extend the good years of life — the ones lived without rush, in good health, fully present, with the people we love. Every dollar, every data point and every idea humanity contributes here moves us closer to that horizon. If you want to get there, you are already part of the cause.
Join the cause →How we'll do it
Three complementary ways to feed the system.
Anyone can contribute through any of the three. Combined, they accelerate everything.
02
Donating clinical and life data
Citizens who share — anonymously, encrypted, revocable at will — their genome, biomarkers, clinical records, vitals, habits and environment. Without this data there is no real science.
03
Sharing discoveries and technology
Researchers, scientists, engineers and journalists contributing datasets, software systems, papers, models, clinical findings or outreach. Everything integrates into one common system.
The system accepts datasets, software systems, research, devices and anything that adds up to the goal. What already exists isn't reinvented — it's integrated.
The system
Human Longevity Operating System: a digital biological twin of humanity.
A layered architecture that takes real data, computes biological age per organ, models causality and simulates interventions safely.
Layer 1
Human data
Genome, epigenome, transcriptome, proteome, metabolome, microbiota, biomarkers, medical imaging, wearables, clinical history, diet, environment and behavior.
Layer 2
Biological age per organ
Tissue-level biological clocks: brain, immune, muscle, liver, heart, kidney and endocrine. Not a single age — the functional age of each system.
Layer 3
Causal model
Bayesian networks, causal models and graph neural networks to identify which mechanisms actually drive aging, not just what correlates with it.
Layer 4
Intervention simulator
Virtually test senolytics, partial reprogramming, mitochondrial therapies, somatic editing and geroprotectors before touching a real person.
Layer 5
Safety and bioethics
Continuous risk assessment: cancer, fibrosis, immune failure, loss of cell identity, neurological damage. What isn't safe doesn't move forward.
Layer 6
Healthy longevity prediction
Not just living longer — reaching 90, 100 or 110 years with cognition, muscle strength, immunity and cellular repair intact.
Longevity Node — the system endpoint
A wearable + patch + app + integrated lab, connected to your personal medical record and the central model.
- Daily capture of vitals, sleep, glucose, heart rate and HRV, temperature and oxygen.
- Periodic blood, epigenetic, proteomic, metabolomic and immune profiles.
- Scheduled medical imaging: MRI, DEXA, ultrasound, cardiovascular and brain imaging.
- Connected clinical record with dynamic consent, encrypted data, identity-from-biology separation.
- Personal longevity AI returning plain-language reports and recommendations.
What we integrate
Ten scientific disciplines on a single platform.
Aging cannot be understood from one science alone. Human Aging Simulators (HAS) spans from DNA to behavior and bioethics.
Human genomics
Variants associated with longevity, DNA repair, telomeres, somatic mutations and cancer risk.
Epigenomics
DNA methylation, histone modifications, epigenetic clocks and Yamanaka-style partial reprogramming.
Transcriptomics
Which genes turn on or off with age, with tissue-level differences: brain, muscle, liver, skin, blood.
Proteomics
Protein changes, inflammation, cell signaling and per-organ proteomic clocks.
Metabolomics
NAD+, glucose, lipids, amino acids, mitochondria, insulin sensitivity and oxidative damage.
Cellular aging biology
Cellular senescence, autophagy, proteostasis, mitochondrial dysfunction and stem-cell exhaustion.
Immunology
Inflammaging, immunosenescence and immune surveillance against cancer.
Systems biology + AI
Multi-omic models, gene regulatory networks, biological digital twins and intervention simulation.
Regenerative medicine
Stem cells, gene therapies, partial reprogramming and tissue regeneration.
Bioethics and safety
Tumor risk, restricted germline editing, biological inequality, consent and genetic control.
Benefits per role
What each person gets back for contributing.
Every contribution is acknowledged, documented and returned as concrete value.
For those who contribute financial donations
Donors fund the infrastructure that holds everything up: sequencing, compute, validation, grants and operations.
- Monthly reports on scientific, technical and financial progress.
- Official recognition as principal donors of the human longevity cause.
- Full traceability: see how every dollar was spent and what result it produced.
- Early access to relevant findings before they are published openly.
For those who share their data
Anyone can upload clinical, genomic, biometric and lifestyle data — encrypted, anonymous, revocable — and receive personalized science back.
- Personal reports on clinical, genomic and statistical progress.
- Per-organ biological age and your personal aging speed.
- Nutrition, exercise and prevention recommendations based on your data.
- Free access to every tool the system builds for your healthy longevity.
For researchers, scientists and journalists
Any professional who contributes datasets, systems, papers, clinical findings or outreach is integrated and credited as an author.
- Official recognition as a contributor to the discoveries you helped produce.
- Co-authorship on papers published in bioRxiv with open peer review.
- Access to datasets, public API, MCP and project compute.
- Public visibility in monthly reports and the collaborators wall.
Privacy and consent
Stricter than any social network. More transparent than any pharma company.
A person's genome also reveals information about their family. Governance matters as much as the science.
- Dynamic informed consent: change your mind whenever you want.
- Pseudonymized, end-to-end encrypted data, separated from your identity.
- No selling to insurers, employers or third parties for commercial use.
- Right to leave the study and erase your data at any time.
- Independent bioethics committee with external audit and public reporting.
- Germline editing forbidden. No proprietary therapies. No corporate capture.
Phased roadmap
From landing to global open scientific infrastructure.
We are in Phase 1. Each phase is validated locally before committing cloud resources.
Phase 1 — Active
Landing & early traction
Public page, financial transparency, first donations, citizens and collaborators onboarded. Real-demand validation.
Phase 2 — Next
Data pipeline & synthetic population
Global synthetic cohorts based on public aggregates, first dataset on Zenodo, first paper on bioRxiv.
Phase 3
Digital biological twin
Per-organ biological age, intervention simulators, first version of the Longevity Node and personalized reports for citizens.
Phase 4
Public API + MCP + global community
Open API and MCP server so any researcher or external LLM can plug into the system with traceable citations.
Non-negotiable principles
How we work.
Open science
MIT/Apache code, CC-BY data and content. Everything is released so the community can audit, replicate and extend it.
Transparency
Every decision, every dollar and every finding is documented and published. Monthly open reports — no opacity.
Ethical AI
Auditable models, explainable decisions, no manipulation or discrimination. Independent bioethics committee with external audit.
Humanity first
Every decision puts human benefit before commercial gain. No proprietary patents, no corporate capture, no lock-in.
Reproducible research
Every method, dataset and result is published so any team can replicate it step by step. Science that can't be replicated isn't science.
Anonymized data
End-to-end encryption, identity separated from biology, no sale to insurers or third parties. Your data stays yours.
Global access
Multilingual, free and available to any country, hospital or person on the planet. Longevity must not be a privilege.
Not a medical device
Human Aging Simulators (HAS) is educational and research-oriented. It does not diagnose, treat or replace clinical advice. Labeled visibly, always.
Current status & transparency
We are on day one. In public. And that's good news.
Human Aging Simulators (HAS) is at concept stage: solo founder, self-funded, no external funding yet. That means anyone arriving now — you, today — joins while there is still everything to build, and your name can stay in the foundations forever.
If you believe an open, global, multidisciplinary system to extend the good years of human life is something the world needs, there are three immediate ways to push it: donate, share your data or collaborate. Any one of them already counts.
- Stage
- Concept / Pre-V1
- Team
- Solo founder + early volunteers
- Funding
- Bootstrap + open donations
- Transparency
- Monthly public reports from day one
More good years of life are possible. We just need many people to say yes — today.
Any of the three paths is already a real step. The three together make it happen sooner, for more people.